Phụ lục K
K. Research landscape and bibliometrics
How much alternative-protein research Vietnam publishes, topic by topic and against its neighbours, which groups and institutions hold the relevant skills, who funds them, and the 11 research gaps Vietnam is well placed to fill.
Nội dung trang này bằng tiếng Anh. Đọc bản tóm tắt tiếng Việt
Trong trang này
- K.1 Key findings
- K.2 How the counts were made
- K.3 Topic-by-topic depth
- K.4 Regional benchmark
- K.5 Trend
- K.6 Vietnam's adjacent strengths
- K.7 Representative papers
- K.8 Institutions and their capabilities
- K.9 International collaborations
- K.10 Research funding programmes
- K.11 Eleven research gaps Vietnam is well placed to fill
- K.12 Retraction and data-quality flags
- K.13 Method notes: Scite and OpenAIRE
- Gaps and how to close them
- Related data files
This appendix maps Vietnam's published research relevant to alternative protein: how much there is, where it sits, who does it, who pays for it, and where the gaps are. It combines two passes:
- Wave 1 (Scite): 30 searches in the Scite literature database, more than 150 Vietnam-affiliated records from 2015 to 2026 screened, and 76 papers tabulated with a key result each 1 .
- Wave 2 (OpenAIRE): country-tagged counts for 20 topics in Vietnam and 3 topic groups in five comparison countries, with every query URL stored so that the counts can be re-run 2 .
publications.csv (103 rows) merges the wave 1 list with 40 top-cited wave 2 records, deduplicated on DOI. The technology science itself (titres, costs, safety) is in J. Science; pilot plants, laboratories and graduates are in L. Labs and talent.
Terms: VN-affiliated means at least one author works at a Vietnamese institution. VN-tagged means OpenAIRE links the record to Vietnam through its country code. Per 10k means topic records per 10,000 of the country's total OpenAIRE publication records in the same window. DIAAS and PDCAAS are protein-quality scores that correct amino-acid content for digestibility.
K.1 Key findings
- Vietnam's output on food-facing alternative protein is small. Records tagged to each country for plant-based or cultivated meat, 2015 to September 2026: Vietnam 9, Philippines 10, Indonesia 47, Thailand 49, Malaysia 61, Singapore 112 2 . Vietnam has about 5 to 12 times fewer records than Indonesia, Thailand, Malaysia and Singapore (our calculation: 47 / 9 = 5.2; 112 / 9 = 12.4).
- The gap remains after adjusting for research size. Per 10,000 publications: Vietnam 0.37, Philippines 0.62, Malaysia 1.02, Thailand 1.58, Singapore 2.94 2 . Vietnam's intensity is about a quarter of Thailand's and an eighth of Singapore's (our calculation from the same counts). Edition 1.1 adds a second database: on a broader core basket, OpenAlex gives 4.1 works per 10,000 national publications for Vietnam against 13.4 for Thailand (2015 to 2025), about 31% 3 . We therefore say "about a quarter to a third of Thailand's".
- In feed-side protein, Vietnam is at the regional level. Fishmeal-replacement records per 10,000: Vietnam 0.42, Thailand 0.45, Malaysia 0.47, Philippines 0.68 2 . The Vietnam figure is an undercount: a broader wave 1 search found about 20 Vietnamese aquafeed replacement papers 1 .
- Vietnam has zero or near-zero records in six core technologies after reading the titles: precision fermentation (0), mycoprotein (0 to 1), fish or shrimp cell lines for food (0), cultivated meat (1, a legal analysis), texturised or extruded protein (1, a 2026 review) and mung bean protein (0 to 1) 2,1 .
- Plant-based meat research is about 5 on-topic papers from 2015 to 2026, and no Vietnamese extrusion study (edition 1.1: the one candidate is Taiwanese; see the correction below) 2,3 .
- Vietnam's real strengths sit next to alternative protein: aquafeed nutrition trials (Can Tho University, Nha Trang University), Pichia pastoris expression (VNU-HCM University of Science), human stem-cell culture including serum-free media (Vinmec, VNU-HCM Stem Cell Institute), fungal genetic tools for koji mould and Cordyceps (VNU Hanoi University of Science) and microalgae cultivation (Institute of Biotechnology VAST, VNUA) 1 .
- Spirulina is Vietnam's biggest topic (87 records, 3.62 per 10,000), but the most-cited papers are about wastewater, diesel-engine fuel and nanoparticles; only one surfaced paper extracts spirulina protein as an ingredient 2 .
- Output is rising from a very low base: 7 records in 2015 to 2019, 14 in 2020 to 2022 and 21 in 2023 to September 2026, across the topic sets read in full 2 .
- No Vietnamese DIAAS or PDCAAS study was found, although Vietnamese groups do measure in vitro digestibility, RNA reduction and aflatoxin 1,4,5,6 .
- Research money is national and small-grant based. NAFOSTED is the funder most often acknowledged; international money (ACIAR, SATREPS, EU, Dutch) is present but not aimed at alternative protein; no GFI grantee in Vietnam was found 7,8,9,10 .
K.2 How the counts were made
K.3 Topic-by-topic depth
Depth scale: none; thin (a few isolated papers, no sustained group); moderate (one or more groups publishing repeatedly); strong (several groups, international-level output). Wave 1 counts are Vietnam-affiliated papers found and screened in Scite; wave 2 counts are OpenAIRE VN-tagged records from 1 January 2015 to 23 September 2026, with records per 10,000 of Vietnam's 240,387 publications 1,2 .
| Topic | Wave 1 (Scite, screened) | Wave 2 (OpenAIRE raw count, per 10k) | Wave 2 after reading titles | Depth | Leading Vietnamese groups |
|---|---|---|---|---|---|
| Plant protein extraction and functionality (rice, rice bran, broken rice, distillers' grains, legumes, seeds) | 12 to 15 | Rice protein 1 (0.04); mung bean protein 1 (0.04); SPI or SPC 9 (0.37) | Rice: 1 (HUST papers missed); mung bean: 0 to 1; soy protein: 4 aquafeed, 2 food, 3 other | Thin | HUST; HCMUT; IBT VAST; IU VNU-HCM |
| Texturisation, extrusion, meat analogues | 2 plus 1 review | Plant-based meat 9 (0.37); textured or extruded protein 1 (0.04) | Plant-based meat about 6 on-topic (2 reviews, extrudate texture, soy burger, meat-reduced sausage, methyl cellulose and guar gum cooking study); textured protein: 1 review (2026) | Thin; at most one extrusion study | Not concentrated in one group |
| Fungal biomass, mycoprotein, koji, tempeh | 6 to 8 | Mycoprotein or fungal biomass 11 (0.46); A. oryzae 23 (0.96); tempeh or mycoprotein 4 (0.17) | Mycoprotein 0 to 1 (rest is biosorption); A. oryzae: genetic tools and enzymes; tempeh: 0 Vietnamese research | None for mycoprotein and tempeh; moderate for fungal genetic tools | VNU Hanoi HUS; HUST (traditional starters) |
| Yeast and bacterial single-cell protein; agro-waste to protein | 6 to 8 | Single-cell protein 6 (0.25) | 3 real, one of them retracted (plus its duplicate record) | Thin | HUST (spent yeast); VNU Hanoi IMBT (methanotroph) |
| Recombinant protein expression (precision fermentation hosts) | About 25 (83 Scite affiliation hits) | Pichia 25 (1.04); precision fermentation 1 (0.04) | Pichia: vaccine antigens and enzymes, no food protein in the top 10; precision fermentation: 0 | Moderate for pharmaceutical and enzyme proteins; none for food proteins | VNU-HCM University of Science; IBT VAST; VNU Hanoi HUS |
| Microalgae | 30 to 40 | Spirulina 87 (3.62); microalgae protein 3 (0.12) | Spirulina: top-cited are environment and fuel; microalgae protein: 3 network papers | Moderate for cultivation, wastewater and lipids; thin for protein as an ingredient | IBT VAST; VNUA; VAST chemistry and environment groups; HCMUTE |
| Seaweed protein | 3 to 5 | 1 (0.04) | 1 (feed) | Thin; none for food protein extraction | Can Tho University |
| Duckweed, Wolffia, azolla | About 8 | 23 (0.96) | Genomics and taxonomy | Thin; none for protein | Can Tho University journal survey; Vietnamese authors with IPK Gatersleben; AGI VAAS |
| Mushrooms and mycelium | About 40 on cultivation and bioactives; 2 to 3 on protein | not run | n/a | Moderate for cultivation; thin for mycelium as food | VNUA mushroom group |
| Cell culture for cultivated meat | 0 technical papers; more than 50 on human stem cells and scaffolds; 1 on livestock stem cells | Cultivated meat 1 (0.04); fish or shrimp cell line 1 (0.04) | Cultivated meat: 1 legal paper; cell line: 0 (a toxicology paper) | None for cultivated meat; strong for adjacent human cell therapy | Vinmec; VNU-HCM Stem Cell Institute; IU VNU-HCM |
| Insect protein (benchmark) | About 10 | Black soldier fly 34 (1.41) | Biodiesel plus feed | Thin to moderate | VNUA |
| Alternative protein in aquafeed | About 20 | Fishmeal replacement 10 (0.42); "alternative protein" 20 (0.83) | Fishmeal replacement: about 7 Vietnamese trials, 2 doubtful tags; "alternative protein": mostly feed | Moderate | Can Tho University; Nha Trang University (RIA1 to RIA3 not visible) |
Two query notes matter for re-runs 2 . "Koji" was dropped from the A. oryzae query because it matched the Japanese given name Koji in author fields (169 hits). A first textured-protein query that included "textured protein" OR "texturized protein" broke the search and returned the whole Vietnam total; it was discarded.
K.4 Regional benchmark
OpenAIRE records, 2015 to September 2026, with records per 10,000 of each country's total 2 :
| Country | Total publications | Novel-food basket (plant-based + cultivated meat) | Spirulina / Arthrospira | Fishmeal replacement |
|---|---|---|---|---|
| Vietnam | 240,387 | 9 (0.37) | 87 (3.62) | 10 (0.42) |
| Thailand | 310,198 | 49 (1.58) | 164 (5.29) | 14 (0.45) |
| Malaysia | 598,148 | 61 (1.02) | 178 (2.98) | 28 (0.47) |
| Indonesia (see note) | 2,667,071 | 47 (0.18) | 928 (3.48) | 27 (0.10) |
| Philippines | 161,138 | 10 (0.62) | 36 (2.23) | 11 (0.68) |
| Singapore | 380,453 | 112 (2.94) | 28 (0.74) | 6 (0.16) |
Notes. The basket query is "plant-based meat" OR "meat analogue" OR "cultured meat" OR "cultivated meat". Only Vietnam's titles were screened; the other countries' counts are raw. Indonesia's total is inflated by OpenAIRE's indexing of national open journals, so its per-10k figures understate its intensity 2 . OpenAIRE has no "group by" function, so each country and topic needs a separate query; China and South Korea were not run.
Readings:
- Vietnam's weakness is specific to novel food technologies. In algae and in aquafeed protein replacement it is at the regional level, and probably above it once the undercount is corrected 2,1 .
- Singapore's profile is the mirror image: strong on novel food, weak on feed and algae 2 .
- A realistic five-year aim would be for Vietnam's novel-food basket intensity (0.37 per 10,000) to reach the Philippines (0.62) or Malaysia (1.02) 2 . This is the wave 2 agent's suggestion, not a policy target.
K.5 Trend
Year counts could be built only for the topic sets small enough to read in full (plant-based meat, textured protein, rice protein, soy protein, single-cell protein, tempeh or mycoprotein, cultivated meat, microalgae protein, seaweed protein, fishmeal replacement): 42 unique DOIs 2 .
| Year | 2015 | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | 2026 (to Sept) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Records | 0 | 3 | 0 | 2 | 2 | 4 | 5 | 5 | 6 | 5 | 6 | 4 |
By period: 7 records in 2015 to 2019, 14 in 2020 to 2022 and 21 in 2023 to September 2026 2 . The counts include false positives, so read them as direction only. Year splits for the larger sets (spirulina, black soldier fly, Pichia, A. oryzae, duckweed, "alternative protein") need OpenAlex.
K.6 Vietnam's adjacent strengths
Aquafeed protein replacement is the deepest applied field, with measured results from laboratory or tank trials 15,16,17 :
- soy protein concentrate replaced 40% of fishmeal protein in snakehead with no loss of growth; 60 to 100% replacement reduced growth (2016);
- fermented soybean meal had 88.8% crude protein digestibility in whiteleg shrimp, with an optimum fishmeal replacement of 253.6 g/kg (2018);
- spent brewer's yeast replaced up to 60% of fishmeal protein in giant freshwater prawn without loss of growth or survival (2019).
Food-grade side-stream protein (HUST) 18,4,19 :
- rice-based dried distillers' grains from Vietnamese ethanol plants hold 55 to 80% protein (dry matter); cassava distillers' grains only 13 to 16% (preprint, 2024);
- alkaline extraction recovered 90% of the protein, and enzymatically extracted protein was 77.1% digestible in vitro (2025);
- spent brewer's yeast protein was recovered at 84.9% and made into an energy bar with 14.9 g protein (2024).
Recombinant growth factors and serum-free culture 20,21,22,23 . VNU-HCM groups expressed FGF-2, KGF/FGF7 and PDGF-BB in Pichia (2020 to 2021). Vinmec tested serum- and xeno-free media for cord-blood stem cells; only 1 of 4 commercial kits (StemMACS) worked (2022). These are the costliest ingredients of cultivated-meat media, made here for medicine, not food.
Fungal genetic tools 24,25 . VNU Hanoi University of Science built an Agrobacterium-mediated transformation system with dual auxotrophic markers in A. oryzae (2021) and reached 100% pyrG deletion efficiency in five Cordyceps militaris strains, the base for a food-grade expression platform (2024).
Microalgae cultivation 26,27 . A salt-tolerant Spirulina strain reached 48.73% protein (dry weight) in a 42 ppt medium (2023). VNUA published a review of Arthrospira production in Vietnam (2021).
Mid-sized clusters that sit next to alternative protein (OpenAIRE, VN-tagged): black soldier fly 34 records (the four most cited are about biodiesel from larval fat), Pichia 25 (mostly vaccine antigens and enzymes), A. oryzae 23 (mostly fungal genetic tools), duckweed 23 (mostly genomics and taxonomy) and "alternative protein" 20 (mostly feed) 2 . None of the ten most-cited papers in the Pichia, A. oryzae or duckweed clusters produces a food protein.
K.7 Representative papers
A selection from publications.csv. Citation counts are OpenAIRE counts from wave 2 where available. "Probable" means the institution was inferred from the author group, not read from the paper header 1,2 .
| DOI | Year | Topic | Institution | Key result | Citations | Evidence |
|---|---|---|---|---|---|---|
| 10.1002/apj.70043 | 2025 | Rice distillers' grain protein | HUST | 90% alkaline extraction; enzyme-extracted protein 77.1% digestible in vitro | n/a | 4 |
| 10.21203/rs.3.rs-3171967/v1 | 2024 | Rice distillers' grain | HUST | 55 to 80% protein (dry matter); preprint | n/a | 18 |
| 10.51316/jst.178.etsd.2024.34.5.4 | 2024 | Spent brewer's yeast protein | HUST | 84.9% protein recovery; energy bar with 14.9 g protein | n/a | 19 |
| 10.15625/2525-2518/55/5a/12192 | 2018 | Yeast RNA reduction | HUST (probable) | Nucleic acid reduction in spent-yeast hydrolysate | n/a | 5 |
| 10.1016/j.ifset.2021.102692 | 2021 | Rice protein recovery | HCMUT (probable) | Ultrafiltration recovery of rice protein | 22 | 28,2 |
| 10.15625/0866-7160/v37n4.7091 | 2016 | Rice bran protein isolate | IBT VAST | Laboratory method for rice bran protein isolate | n/a | 29 |
| 10.1111/ijfs.17089 | 2024 | Hybrid meat | not established | 10 to 15% of meat replaced with germinated mung bean flour was accepted in sausage | 9 | 30,2 |
| 10.17113/ftb.63.01.25.8629 | 2025 | Plant-based meat | not established | Mangosteen peel extract extends the shelf life of soy burgers | 3 | 31,2 |
| 10.1093/ijfood/vvae080 | 2025 | Meat-analogue extrudates | Taiwan (verified in edition 1.1) | The only VN-tagged extrusion experiment; all three authors at National Pingtung University of Science and Technology, so not Vietnamese | 9 | 2,3 |
| 10.1111/jfpe.70365 | 2026 | Plant-based fish analogues (review) | first author with a Vietnamese name; affiliation not verified | Review | 0 | 32,2 |
| 10.15625/1811-4989/14/3/9876 | 2016 | Methanotroph single-cell protein | VNU Hanoi IMBT | Methane-oxidising bacterium isolated; no follow-up found | 1 | 33,2 |
| 10.20944/preprints202503.1319.v1 | 2025 | Fungal fermentation of cassava residue | not established | Pleurotus mycelium on cassava plus soy residue raised protein 1.84-fold; preprint | n/a | 34 |
| 10.1007/s12649-022-01724-x | 2022 | Cassava bagasse with Aspergillus co-culture | not verified | Closest item to cassava-to-protein; protein enrichment not yet checked | 8 | 2 |
| 10.1007/s11274-021-03060-z | 2021 | A. oryzae genetic tools | VNU Hanoi HUS (probable) | Dual-auxotrophic transformation system | 13 | 24,2 |
| 10.1007/s11274-017-2275-9 | 2017 | A. oryzae genetic tools | VNU Hanoi HUS (probable) | Uridine/uracil auxotrophs | 43 | 2 |
| 10.47371/mycosci.2024.10.003 | 2024 | Cordyceps expression platform | VNU Hanoi HUS (probable) | 100% pyrG deletion efficiency in five strains | n/a | 25 |
| 10.15625/vjbt-21940 | 2025 | Pichia phytase for aquafeed | VNU-HCM US (probable) | Secreted alkaline phytase active at pH 7.5 | n/a | 35 |
| 10.32508/stdj.v23i2.1746 | 2020 | FGF-2 in Pichia | VNU-HCM US | Multi-copy secretory expression | n/a | 20 |
| 10.32508/stdjet.v4i3.858 | 2021 | PDGF-BB in Pichia | VNU-HCM | Fed-batch strategies | n/a | 21 |
| 10.1186/s13104-017-2471-6 | 2017 | Pichia versus S. cerevisiae | VNU-HCM (probable) | Host comparison | 42 | 2 |
| 10.1186/s13287-021-02694-y | 2022 | Serum- and xeno-free media | Vinmec | 1 of 4 commercial kits worked for cord-blood stem cells | n/a | 23 |
| 10.1262/jrd.2019-050 | 2019 | Porcine germline stem cells | IU VNU-HCM (probable) | The only livestock stem-cell paper found | n/a | 36 |
| 10.2478/vjls-2024-0013 | 2024 | Cultivated meat regulation | legal scholars | EU and Singapore rules, implications for Vietnam; the only Vietnamese cultivated-meat paper | 0 | 37,2 |
| 10.3390/su151511906 | 2023 | Salt-tolerant Spirulina | IBT VAST | 48.73% protein (dry weight) in 42 ppt medium | n/a | 26 |
| 10.54644/jte.70b.2022.1213 | 2022 | Spirulina protein extraction with cellulase | HCMUTE (journal) | The only spirulina protein-as-ingredient item surfaced | 5 | 2 |
| 10.22144/ctu.jen.2022.029 | 2022 | Duckweed diversity | Can Tho University journal | Over 100 wild duckweed samples collected nationwide | n/a | 38 |
| 10.1038/s41598-020-75728-9 | 2020 | Duckweed genome | Vietnamese first author with IPK Gatersleben | Chromosome-scale Spirodela intermedia genome | 37 | 39,2 |
| 10.1111/are.13147 | 2016 | SPC in snakehead feed | Can Tho University | 40% of fishmeal protein replaced without growth loss | 23 | 16,2 |
| 10.1111/anu.12648 | 2018 | Fermented soybean meal in shrimp feed | Nha Trang University (probable) | 88.8% protein digestibility; optimum 253.6 g/kg replacement | n/a | 15 |
| 10.1111/anu.12915 | 2019 | Brewer's yeast in prawn feed | Can Tho University with Swedish partners | Up to 60% of fishmeal protein replaced | n/a | 17 |
| 10.1007/s10811-018-1457-7 | 2018 | Seaweed protein in shrimp feed | Can Tho University | Cladophora protein partly replaced fishmeal in black tiger shrimp postlarvae | 25 | 40,2 |
| 10.3390/aquacj5010007 | 2025 | Black soldier fly larvae in eel feed | VNUA | 30% larvae meal best in swamp eel; feed conversion ratio 2.33 | n/a | 41 |
| 10.3390/foods11111531 | 2022 | Catfish side-stream protein | Nha Trang University | pH-shift recovery of protein from tra catfish side streams | n/a | 42 |
| 10.47866/2615-9252/vjfc.4588 | 2025 | Traditional soy sauce safety | NIFC journal | Aflatoxin tested in 38 tương (fermented soybean paste) samples | n/a | 6 |
K.8 Institutions and their capabilities
Summary from institutions.csv (31 rows). Location is the current province 1 .
| Institution | Location | Relevant capability | Evidence strength | Sources |
|---|---|---|---|---|
| Hanoi University of Science and Technology (HUST), biotechnology and food technology | Hanoi | Protein extraction and characterisation (SDS-PAGE, DSC, in vitro digestibility); enzymatic hydrolysis; yeast fermentation; ethanol processes | Medium; strongest group on food-grade side-stream protein | 18,4,5,19,43 |
| VNU Hanoi University of Science (HUS), fungal molecular biology | Hanoi | A. oryzae, Penicillium and Cordyceps transformation and markers | Medium; attribution probable | 24,25 |
| VNU Hanoi Institute of Microbiology and Biotechnology (IMBT) and the Vietnam Type Culture Collection (VTCC) | Hanoi | Culture collection supplying strains used in Vietnamese papers; methanotroph isolation | Medium | 1,33 |
| VNU-HCM University of Science (HCMUS) | Ho Chi Minh City | Pichia expression (multi-copy strains, fed-batch); growth factors; bacteriocins; phytase; CRISPR yeast | Medium | 35,20,21,22 |
| Stem Cell Institute, VNU-HCM University of Science | Ho Chi Minh City | Stem-cell isolation and expansion, spheroids, scaffolds | Medium; human biomedical focus | 44 |
| Vinmec Research Institute of Stem Cell and Gene Technology | Hanoi | GMP-oriented stem-cell culture; serum- and xeno-free media testing | Medium; no food or animal-cell work | 23,45 |
| VNU-HCM International University (IU), School of Biotechnology | Ho Chi Minh City | Germination, starch and protein chemistry; porcine germline stem cells | Low; attribution from author groups | 36 |
| Ho Chi Minh City University of Technology (HCMUT) | Ho Chi Minh City | Ultrafiltration of rice protein; fermentation of defatted rice bran | Medium | 28 |
| Institute of Biotechnology (IBT), VAST | Hanoi | Microalgae strain collection and cultivation; Pichia and A. niger expression; rice bran protein isolate | Medium | 26,29 |
| Vietnam National University of Agriculture (VNUA) | Hanoi | Mushroom strains and cultivation; spirulina; fish and poultry feeding trials | High (880 Scite affiliation records) | 27,1 |
| Can Tho University (CTU), College of Aquaculture and Fisheries | Can Tho | Fish and shrimp nutrition and digestibility trials; seaweed and Artemia protein; duckweed germplasm survey | High; strongest publisher on alternative aquafeed protein | 46,16,17,40 |
| Nha Trang University (NTU) | Khanh Hoa | Fish side-stream protein (pH-shift); hydrolysates; marine fish nutrition trials | Medium (183 Scite affiliation records) | 15,42,47 |
| Food Industries Research Institute (FIRI), under MOIT | Hanoi | Online microbial culture collection; pilot production and technology transfer centre; enzyme and protein technology department; accredited testing | High for structure; equipment sizes not published | 48 |
| National Institute for Food Control (NIFC), under MOH | Hanoi | Mycotoxin, contaminant and nutritional analysis (aflatoxin limit of detection 0.74 µg/kg reported in its journal) | Medium | 6 |
| Agricultural Genetics Institute (AGI), VAAS | Hanoi | Duckweed regeneration and transformation (vaccine antigen) | Low; attribution probable | 1 |
| Research Institutes for Aquaculture No. 1, 2 and 3 (RIA1 to RIA3), under MAE | Bac Ninh; Ho Chi Minh City; Khanh Hoa | Aquaculture research; nutrition work not visible in Scite | Low | 1 |
| Ho Chi Minh City Biotechnology Center | Ho Chi Minh City | Claimed pilot fermentation services (not verified; see L. Labs and talent) | Low | 1 |
Named institutions with no relevant output found in the Scite search: University of Danang, IUH, Van Lang, VinUni, RMIT Vietnam, Fulbright, Phenikaa, Hue University (one unconfirmed attribution), the Field Crops Research Institute (breeding only), and Nong Lam University (not searched by affiliation) 1 . This is evidence of low visibility in indexed journals, not proof that they do no relevant work.
A count-based institution ranking was not possible without OpenAlex. The wave 2 qualitative order, built from wave 1 attributions and the DOIs surfaced, is: VNU Hanoi HUS (A. oryzae tools), VNU-HCM HCMUS (Pichia), IBT VAST (microalgae), HUST (side-stream protein), Can Tho University (aquafeed), Nha Trang University (aquafeed), VNUA (spirulina, black soldier fly), HCMUT (rice protein), VNU Hanoi IMBT (methanotroph), HCMUTE (spirulina protein) 2 . HUST is under-represented in OpenAIRE's Vietnam tag.
After the 2025 reforms, RIA1 to RIA3 and VAAS sit under the Ministry of Agriculture and Environment (MAE), FIRI under MOIT, NIFC under MOH and NAFOSTED under MOST 1 . These mappings were not re-verified.
K.9 International collaborations
| Partner | Vietnamese partner | Topic | Evidence |
|---|---|---|---|
| Wageningen University and Research (Netherlands) | Can Tho University | Pangasius digestion and faecal waste; seaweed for livestock methane reduction (2022 seed study) | 10.1111/anu.12632; 10.18174/566553 49,50 |
| Swedish University of Agricultural Sciences (SLU) | Can Tho University | Brewer's yeast replacing fishmeal and soybean meal in prawn and tilapia | 10.1111/anu.12915; 10.3390/aquacj4040019 17,51 |
| Deakin University (Australia) | Nha Trang University | High plant-protein diets with fish protein hydrolysate in barramundi | 10.1111/anu.13404 47 |
| Agreenium / Institut Agro Dijon (France), Erasmus+ AsiFood | HUST and others | Tropical Fermentation Network: starters, safety, by-product use | 10.3389/fmicb.2018.02278 43 |
| IPK Gatersleben (Germany) | Vietnamese duckweed researcher | Duckweed genomics | 10.1038/s41598-020-75728-9 39 |
| German partners | VAST | Fungal strain collection from Vietnam | 10.1371/journal.pone.0202695 52 |
| Belgian partners | Vietnamese authors | Microalgae isolated from shrimp ponds for food, feed and biodiesel | 10.3390/en13040898 53 |
| Japanese universities, SATREPS (JST-JICA) | various | Biomass energy at a shrimp farm (Ben Tre); indigenous pig genetics; cassava mosaic disease | Scite acknowledgements 1,54 |
| ACIAR (Australia) | various | Grouper manufactured feed; pangasius food loss | 9 |
| Ghent University (Belgium) | Can Tho University | Artemia and shrimp health (not protein) | Scite acknowledgements 1 |
| FiBL (Switzerland) | Binca Seafoods (prior lead) | Duckweed | No Vietnam publication found; FiBL duckweed papers are European trials 55 |
| Japanese koji partners; Korean institutes | none found | none | Gap 1 |
The share of Vietnamese papers with international co-authors was not measured: OpenAIRE returned no affiliations 2 . Qualitatively, the most-cited VN-tagged records in microalgae, spirulina and black soldier fly come from international networks (Malaysia-led microalgae groups, a Taiwan-based black soldier fly biodiesel group, the IPK duckweed network) 2 . Work led from inside Vietnam on protein ingredients typically has 0 to 25 citations 2 .
K.10 Research funding programmes
From research_funding.csv (16 rows). Capital-side programmes (venture funds, NATIF loans, philanthropic RFPs for companies) are in M. Capital.
| Programme | Funder | Relevant scope | Amount | Status in 2026 | Evidence |
|---|---|---|---|---|---|
| NAFOSTED basic research grants | NAFOSTED (MOST) | Basic and applied research, technology development, international cooperation | Typical size not established | Operating; the funder most often acknowledged (255 Scite records matched NAFOSTED with protein, fermentation or aquafeed terms) | 7,8 |
| NAFOSTED international joint calls | NAFOSTED with foreign agencies | Joint projects | not established | Category listed; 2025 to 2026 partner calls not verified | 7 |
| Vingroup Innovation Foundation (VINIF) | Vingroup | Research projects (Big Data emphasis); Master's, PhD and postdoctoral support | 2018 to 2023: more than 3,000 scientists supported; about 1,300 Master's and PhD scholarships; 180 postdoctoral fellowships; 117 projects | 2025 to 2026 status not shown; appears in relevant papers mainly as scholarship support | 56,8 |
| Law on Science, Technology and Innovation 93/2025/QH15 | National Assembly | Specialised funds with state capital (Art 6); research-risk exemption (Art 9(3)); controlled testing or sandbox (Arts 21 to 23) | n/a | Issued 27 June 2025; effective date not verified | 57 |
| Resolution 57-NQ/TW (2024) and Resolution 36-NQ/TW (2023) | Politburo | Science, technology and biotechnology budget expansion | Targets not verified; not quoted | In force | 58 |
| Ministerial biotechnology programmes (MAE, MOIT) | Ministries | Agricultural and industrial biotechnology | not established | Decision numbers not retrieved | 58 |
| Provincial science and technology funding | Provincial departments of science and technology (34 provinces) | Applied projects with local industry | not established | Operating; budgets not retrieved | 58 |
| GFI Research Grant Program | Good Food Institute | Plant-based, fermentation, cultivated | USD 27 million or more in 141 grants in 26 countries since 2019 | Not accepting submissions; no grantee in Vietnam or Southeast Asia shown on the page read | 10,59 |
| ACIAR Vietnam programme | Australian Centre for International Agricultural Research | Aquaculture (including grouper manufactured feed), pangasius food loss, cassava disease, livestock | AUD 5.4 million across 23 projects in FY2025-26 | Active; commissioned through Australian partners, not open calls | 9 |
| SATREPS | JST and JICA | Research for development | not established | 203 projects in 60 countries (April 2026); Vietnamese projects on biomass energy and pig genetics, not protein | 54 |
| EU Erasmus+ AsiFood; Horizon Europe | European Union | Fermentation training; collaborative research | not established | AsiFood ended; no Vietnamese alt-protein Horizon Europe participation found | 43 |
| Dutch Nuffic/NICHE fellowships and Top Sector seed money | Netherlands | Pangasius nutrition PhDs; seaweed for methane (2022) | not established | Historical collaboration path to Wageningen | 50,49 |
| Newton Fund (UK), USAID (US) | UK, US | Legacy cooperation | not established | Not verified as live; do not rely on them | 58 |
| KOICA and Korean institutes | Korea | none on alt protein found | not established | Not verified | 1 |
K.11 Eleven research gaps Vietnam is well placed to fill
Each gap meets three tests: Vietnam holds a scarce raw material, species or skill; we found no peer-reviewed work on it by anyone in Vietnam; and a named Vietnamese group already has the adjacent skill 1 .
- Cell lines from striped catfish, whiteleg and black tiger shrimp, Asian seabass, grouper and snakehead for cultivated seafood. No fish or shrimp cell line developed in Vietnam was found 1,2 . Adjacent skills: Vinmec and the VNU-HCM Stem Cell Institute (culture, serum-free media); aquatic virology laboratories.
- Low-cost recombinant growth factors for fish-cell media. FGF-2, KGF and PDGF-BB are already expressed in Pichia at VNU-HCM; nobody has tested them on fish cells or costed them per gram 20,21,22 .
- Fungal biomass protein from cassava pulp and peel with a food-grade safety package (cyanide, mycotoxins, RNA, digestibility). Only a Pleurotus preprint for feed exists 34 . Adjacent skills: the A. oryzae toolkit at VNU HUS, RNA reduction in yeast at HUST, aflatoxin analysis at NIFC.
- Koji (tương) strains as a mycoprotein chassis. Indigenous A. oryzae strains are held at VTCC and FIRI, and genetic tools exist; no biomass-protein study was found 24,48 .
- Rice distillers' grain and broken-rice protein texturisation. Extraction is published (HUST); extrusion and functionality in meat analogues are not 4 .
- Protein extraction and feeding trials with Vietnamese duckweed clones, using the collection of more than 100 wild samples 38 .
- Microalgae protein ingredients from salt-tolerant Spirulina (48.7% protein measured) grown on seawater or brackish water on the south-central coast; only cultivation physiology is published 26 .
- Seaweed protein (Ulva, Caulerpa, Kappaphycus) for food and feed; only small shrimp postlarvae trials exist 40,60 .
- Methanotroph or biogas-derived bacterial protein from pig-farm and cassava-starch biogas; one isolation paper (2016), no follow-up 33 .
- A DIAAS or PDCAAS reference dataset for Vietnamese protein ingredients (rice distillers' grain, mung bean, gac seed, spent yeast, catfish side-stream isolates, spirulina). Nothing found 1 . This is a cheap public good every plant-based and feed play needs; no commercial Vietnamese laboratory offering digestibility assays was found either (L. Labs and talent).
- Bacterial single-cell protein and fungal meal in pangasius and whiteleg shrimp diets. Soy, yeast, black soldier fly and seaweed have been tested; novel microbial meals have not 1 .
Quickest to publish, in the wave 1 agent's judgement: the DIAAS dataset, duckweed protein from the national collection, rice distillers' grain texturisation, and Pichia growth factors tested on fish cells 1 .
K.12 Retraction and data-quality flags
- Retracted. The 2023 paper on single-cell protein and nanocellulose from bamboo cellulose (10.1051/e3sconf/202342009003) is retracted, and a duplicate record of it (10.60692/0q29a-9j360) is still indexed. Both are excluded from every count and capability claim 66,2 .
- Probable false positives among top-cited "Vietnamese" items. A 240-citation 2021 review of plant-based meat analogues (10.1007/s00217-021-03810-1) is VN-tagged, but its author team appears Korea- or Malaysia-based 2 . An 821-citation 2019 microalgae review (10.1016/j.fshw.2019.03.001) is a Malaysia-led network paper with a Vietnamese co-author, not led from Vietnam 2 .
- Doubtful tags inside small topic sets. The single mung bean protein hit is an Indonesian journal study (10.22437/ifstj.v9i1.45748); one fishmeal-replacement hit looks like a wrong Vietnam tag (an Azolla preprint on Etroplus); the Indian-journal trial on Leucaena is a genuine Tra Vinh University study (edition 1.1, 3); two tempeh hits are Indonesian peptide papers 2 .
- Affiliation now checked (edition 1.1). The only VN-tagged extrusion experiment (10.1093/ijfood/vvae080, 2025) is from a Taiwanese university, so we found no Vietnamese extrusion study 3 .
- Preprints. Three wave 1 records are preprints, not peer-reviewed: 10.21203/rs.3.rs-3171967/v1, 10.21203/rs.3.rs-7881609/v1 and 10.20944/preprints202503.1319.v1 18,34 .
- Probable attributions. Many institution attributions in
publications.csvwere inferred from author groups, not read from paper headers; theinstitutionscolumn says "probable" or "not established" where so 1 .
K.13 Method notes: Scite and OpenAIRE
Scite (wave 1) 1
- 30 searches on 23 September 2026. Two modes: an affiliation filter set to "Vietnam" or a named institution, and term searches that include "Vietnam". Hit totals before screening were often very large (for example 12,645 for protein extraction with the Vietnam filter) and are meaningless on their own; only the manual screen counts.
- The affiliation filter is incomplete. For fishmeal replacement it returned 3 papers, while term searches found at least 10 1 .
- Scite returns only the first three authors and no affiliations, so a map of Vietnamese researchers abroad could not be built.
- Livestock Research for Rural Development (LRRD), which holds much Can Tho, Nong Lam and Hue work on duckweed and cassava protein, is only partly indexed.
- Stopping rule: searches stopped when new queries returned mainly the same papers or unrelated chemistry and medicine records.
OpenAIRE (wave 2) 2
- OpenAIRE Graph API v1,
researchProductsendpoint, 16:00 to 16:40 UTC on 23 September 2026. Filter: country code, publication date 1 January 2015 to 23 September 2026, type "publication". The exact URL of every query is inbiblio_counts.csv. - The
searchparameter covers title, abstract and some other fields, so single words that are also names are risky (the "koji" case). - The "publication" type includes non-peer-reviewed items and duplicates, and Indonesia's total is inflated by national journal indexing.
- OpenAIRE returns no affiliations and has no group-by, so institution rankings, co-authorship shares and year splits for large topics were not possible.
OpenAlex (planned re-run). A ready-to-run plan of about 100 OpenAlex queries is kept in the wave 2 working papers. With a free API key (budget USD 1 a day) it would take under an hour and would give the institution top 10, the international co-authorship share (filter on more than one distinct country), year trends for large topics, and China and South Korea as scale references 11 .
Gaps and how to close them
| Gap | Cheapest way to close it |
|---|---|
| Institution ranking, co-authorship share, trends for large topics, China and Korea benchmarks | Get a free OpenAlex API key and run the stored re-run plan (about 100 calls). |
| Vietnamese-language journals only partly indexed | Ask NAFOSTED or the Vietnam Citation Index team for topic counts; screen LRRD 2010 to 2026 for Vietnamese affiliations. |
| Affiliation of the most-cited network papers (the extrusion study was resolved in edition 1.1) | Read the paper headers or OpenAlex institution IDs. |
Probable institution attributions in publications.csv | OpenAlex institution IDs, or read the headers. |
| RIA1 to RIA3 aquafeed trials invisible in Scite | Search Vietnamese-language fisheries journals; call the RIA2 nutrition department. |
| NAFOSTED and VINIF grant sizes and 2026 calls | Latest NAFOSTED call notice and funding-norm circular; VINIF annual report. |
| Resolution 57 and 36 targets; MAE and MOIT biotechnology programme decisions | thuvienphapluat.vn or vanban.chinhphu.vn. |
| Vietnamese researchers abroad | ORCID and LinkedIn searches at Wageningen, NUS and A*STAR, Massey, Ghent, UC Davis and Tufts; ask GFI APAC and NIC. |
| GFI grants in 2025 and 2026 | Re-check the GFI grants page and the planning-grant announcements. |
| Current SATREPS, KOICA and Horizon Europe projects | JST project list, KOICA Vietnam office, EU CORDIS. |
See also Q. Open questions.
Related data files
publications.csv: 103 Vietnam-affiliated or VN-tagged papers with DOI, institution, topic, key result and citation count.biblio_counts.csv: 42 OpenAIRE counts by topic and country, with query strings and URLs.biblio_trend_vn.csv: 132 year-by-topic counts for the Vietnam sets read in full.institutions.csv: 31 institutions with capabilities, example DOIs and contacts.research_funding.csv: 16 national and international research funding programmes.science_facts.csv: technology-level facts used in the corrections above (J. Science).- Working papers:
working-papers/wave1/rnd/andworking-papers/wave2/biblio/.
Nguồn được trích dẫn trong trang
- RD-01 scite.ai literature database. 2026-09-23
- BIB-01 OpenAIRE AMKE. OpenAIRE Graph API v1, researchProducts endpoint
- HSC-01 OpenAlex works API, queried through the OpenAlex MCP connector (no personal identifiers sent). 2026-09-24
- RD-23 Vuong M.-D. et al. Functional characterization of protein from rice-based ethanol by-products for food industry use. 2025
- RD-31 Nguyen T.T.N. Influences of technological hydrolysis condition on nucleic acid content of spent brewer's yeast hydrolysate. 2018
- RD-61 Le T.H.Y. et al. Quality evaluation of Vietnam traditional soy sauce concerning nutritional composition and aflatoxin criteria. 2025
- RD-06 NAFOSTED English site
- RD-12 Scite acknowledgement analysis. Queries. NAFOSTED ... AND (protein OR fermentation ...). 2026-09-23
- RD-04 ACIAR. Vietnam
- RD-02 GFI. Research Grant Program
- BIB-02 OpenAlex developer guide. Authentication
- BIB-03 OpenAlex API, works endpoint
- BIB-04 EMBL-EBI. Europe PMC REST search
- BIB-05 Scite. Scite search_literature test query: cultured, cultivated or cell-based meat, affiliation Thailand, from 2015. 2026-09-23
- RD-46 Nguyen N.V. et al. Utilization of fermented soybean meal for fishmeal substitution in diets of Pacific white shrimp. 2018
- RD-47 Tran M.P. et al. Effects of replacing fish meal with soya protein concentrate. 2016
- RD-48 Nguyen H.Y.N. et al. Spent brewer's yeast as a replacement for fishmeal in diets for giant freshwater prawn. 2019
- RD-22 Nguyen T.-T. et al. Rice-based distillers' dried grains from bio-ethanol production, a potential source of protein for food application. 2024
- RD-32 Nguyen M.Q. et al. Investigation of consumer insights and development of alternative protein-rich products from alcoholic beverage byproducts. 2024
- RD-36 Le H.K. et al. Secretory expression of the recombinant FGF-2 protein in Pichia pastoris carrying multiple copies of target gene. 2020
- RD-37 Tran L.H. et al. Glycerol-methanol and sorbitol-methanol mixed feed strategies for recombinant hPDGF-BB production in Pichia pastoris. 2021
- RD-38 Pham T. et al. Heterologous expression of human KGF/FGF7 in Pichia pastoris. 2020
- RD-39 Nguyen T.L. et al. Optimization of human umbilical cord blood-derived MSC isolation and culture methods in serum- and xeno-free conditions. 2022
- RD-33 Thai H.-D. et al. Development of a new Agrobacterium-mediated transformation system based on a dual auxotrophic approach in Aspergillus oryzae. 2021
- RD-34 Trinh M.T. et al. Efficient generation of uridine/uracil auxotrophic mutants in homokaryotic Cordyceps militaris strains for constructing a food-grade expression platform. 2024
- RD-21 Dang D.H. et al. Transcriptome analysis of Spirulina platensis at different salinity and nutrient compositions for sustainable cultivation in Vietnam. 2023
- RD-20 Nguyen D.B. et al. Arthrospira production in Vietnam: current status and prospects. 2021
- RD-24 Doan N.T.T., Lai Q.D. Ultrafiltration for recovery of rice protein: fouling analysis and technical assessment. 2021
- RD-25 Nguyen T.M.P. et al. Preparation of protein isolated from rice bran. 2016
- RD-26 Le T.K.Y. et al. Meat-reduced sausage substituted with germinated mung bean flour. 2024
- RD-27 Nguyen N.H.K. et al. Influence of mangosteen peel extract on. 2025
- RD-66 Tran Thi Ha M.K. et al. Plant-based fish analogues: advances in formulation, processing, nutrition and market dynamics. 2026
- RD-28 Nguyen T.H.T., Dinh T.H. Isolation of a methane-oxidizing bacterium for the study on single cell protein production from methane. 2016
- RD-29 Doan C.C. Improving nutrition facts of cassava and soybean residue through solid-state fermentation by Pleurotus ostreatus mycelium. 2025
- RD-35 Chau Q.C. et al. Development of a Pichia pastoris strain for secretory production of recombinant alkaline phytase. 2025
- RD-42 Bui L.Q.N. et al. Isolation of female germline stem cells from porcine ovarian tissue and differentiation into oocyte-like cells. 2019
- RD-43 Nguyen X.M.H., Nguyen T.K.A. From lab to table: food safety regulations for cell-cultured meat in the EU and Singapore, implications for Vietnam. 2024
- RD-44 Tran N.B.T. et al. Morphological variation, chromosome number and DNA barcoding of giant duckweed (Spirodela polyrhiza) in Vietnam. 2022
- RD-71 Hoang P.T.N. et al. Chromosome-scale genome assembly for the duckweed Spirodela intermedia. 2020
- RD-50 Nguyen T.N.A. et al. Partial replacement of fishmeal protein with green seaweed (Cladophora) protein. 2018
- RD-54 Nguyen N.T., Tran N.H. Black soldier fly larvae meal as a sustainable alternative to fishmeal in juvenile swamp eel diets. 2025
- RD-52 Nguyen H.T. et al. Protein recovery of Tra catfish protein-rich side streams by the pH-shift method. 2022
- RD-56 Waché Y. et al. Prospects for food fermentation in South-East Asia: Tropical Fermentation and Biotechnology Network at the end of the AsiFood Erasmus+ project. 2018
- RD-41 Pham P.V., Vu N.B. In vitro expansion of mesenchymal stem cells for clinical use. 2016
- RD-40 Le M.H. et al. Differential development of umbilical cord-derived MSCs during long-term maintenance in FBS-supplemented and xeno- and serum-free media. 2021
- RD-10 Can Tho University, College of Aquaculture and Fisheries
- RD-53 Siddik M.A.B. et al. Dietary supplementation of fish protein hydrolysate in high plant protein diets. 2021
- RD-07 Food Industries Research Institute
- RD-58 Tran-Tu L.C. et al. Effect of ingredient particle sizes and dietary viscosity on digestion and faecal waste of striped catfish. 2017
- RD-57 Deolu-Ajayi A.O. et al. Seaweed cultivation in Vietnam for livestock methane reduction: a Top Sector Agri & Food SMP report. 2022
- RD-49 Nguyen H.Y.N. et al. Gradual replacement of soybean meal with brewer's yeast in Nile tilapia diet. 2024
- RD-60 Brandt S. et al. A unique fungal strain collection from Vietnam characterized for high performance degraders of bioecological important biopolymers and lipids. 2018
- RD-62 Luu T.N. et al. Isolation and characterization of two microalgal isolates from Vietnam with potential for food, feed and biodiesel production. 2020
- RD-11 JST SATREPS, project list by country
- RD-59 Stadtlander T. et al. Partial replacement of fishmeal with duckweed (Spirodela polyrhiza) in feed for Eurasian perch and rainbow trout. 2023
- RD-05 Vingroup Innovation Foundation
- RD-08 Law on Science, Technology and Innovation No. 93/2025/QH15, thuvienphapluat.vn
- RD-13 Internal leads, not evidence. AltProtein Vietnam prior drafts (00-prior-leads.md; project doc fermentation-wave-1-pack.md)
- RD-03 GFI. Grants
- RD-51 Nguyen T.N.A. et al. Evaluating Artemia biomass and gut weed (Ulva intestinalis) meal as dietary protein for P. 2023
- SCI-10 Soni P, Pradhan PK, Sood N et al. Development, characterization and in vitro applications of a thymus cell line from Pangasianodon hypophthalmus. 2023
- SCI-12 Anoop BS, Puthumana J et al. Immortalization of shrimp lymphoid cells by hybridizing with the continuous cell line Sf9 leading to the development of 'PmLyO-Sf9'. 2021
- SCI-28 EFSA NDA Panel. Safety of Wolffia globosa powder as a Novel food. 2021
- SCI-30 EFSA NDA Panel. Safety of water lentil protein concentrate from Lemna gibba and Lemna minor. 2023
- SCI-34 Appenroth KJ et al. Nutritional Value of the Duckweed Species of the Genus Wolffia as Human Food. 2018
- RD-30 Ho K.N. et al. Bamboo cellulose based single cell protein and nanocellulose. 2023